Search on: RHO GUANINE NUCLEOTIDE EXCHANGE FACTORS 
Descriptors Found: 1
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Descriptor English:   Rho Guanine Nucleotide Exchange Factors 
Descriptor Spanish:   Factores de Intercambio de Guanina Nucleótido Rho 
Descriptor Portuguese:   Fatores de Troca de Nucleotídeo Guanina Rho 
Synonyms English:   ARHGEF1
Cool-1 Protein
PAK-Interacting Exchange Factor beta
Rho Guanine Nucleotide Exchange Factor (GEF) 1
Rho Guanine Nucleotide Exchange Factor 6
Rho Guanine Nucleotide Exchange Factor 7
Rho Guanine Nucleotide Exchange Factor p115
RhoGEF
beta PIX Protein
betaPIX Protein
p115 RhoGEF
p115RhoGEF
Cool 1 Protein
PAK Interacting Exchange Factor beta
PIX Protein, beta
Protein, Cool-1
Protein, beta PIX
Protein, betaPIX
RhoGEF, p115  
Tree Number:   D12.644.360.325.300.099
D12.776.476.325.300.099
Definition English:   Signaling proteins which function as master molecular switches by activating Rho GTPases through conversion of guanine nucleotides. Rho GTPases in turn control many aspects of cell behavior through the regulation of multiple downstream signal transduction pathways. 
History Note English:   2014 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   55310 
Unique Identifier:   D064067 

Occurrence in VHL:
 

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